Clawing Werewolf: The primary antagonist faction. Formed by a merger between the PMCs Otselotovaya Khvatka and Werewolf. Aiming to take advantage of the massive debts of the War Economy and build a military and economic powerhouse. Led by the Masks, a unit made up of the best mercs in both companies: Pressure (uses Laser weaponry), Torch (uses flame weaponry), Gas (Uses biological warfare), Drone (uses remote weaponry), Claw (Melee specialist) Snuff (supposedly immortal) and their commander Blank. Intend to build a Metal Gear and seize control of indebted central american nation of San Lobos, building military state called "Dead Man's Land". Will use Metal Gear to deter foreign threat and recruit former mercs to build army and "collect" on the debts of multiple nations.
San Lobos Army: Weak and poorly trained. Many defect to Clawing Werewolf under General Domingue's command. Form a small resistance, but overall helpless against Clawing Werewolf and defectors. Could provide support to PCs.
Seal Team Four: A Navy SEAL force deployed to both remove Clawing Werewolf from power and secretly to also eliminate the marxist government of San Lobos and ensure the rise a US-friendly state. Contact was lost early into the mission. Could also support PCs and replace dead characters.
FOXHOUND: In the wake of the end of the War Economy, the US Government re-formed FOXHOUND as a Black-ops unit designed to operate in absolute secret. The PCs and their support team would be this.
Ouroboros: Secret organization formed by renegade PMC officers. Essentially the Anti-patriots. Aim to promote continuous global chaos and warfare. All commanding officers perished during the time of the War Economy, and the organization only consists of one agent, the nanomachine-enhanced super-soldier Snuff, and the AI uploaded into his machines to imitate commanding officers. Snuff believes he is part of a wide-reaching conspiracy, unaware that he is the sole force. Snuff intends to usurp control from Blank and use the Metal Gear to trigger a World War.